IB DCE™

MRI dynamic contrast enhanced (DCE) permeability analysis and pharmacokinetic modeling.

Book a meeting
DCE

Overview

With respect to solid tumor assessment, DCE-MRI has been used extensively in monitoring tumor response to antiangiogenic and vascular disrupting agents, radiotherapy, and chemotherapy. In particular, the transfer constant Ktrans appears to be a useful tool in the investigation of tumor microvascular structure and heterogeneity on a per patient basis. This has the potential to improve sensitivity to subtle drug effects and provide additional understanding of tumor biology. 

imagingBiometrics

Features

  • The IB DCE module performs post-processing of dynamically acquired MR datasets to evaluate image intensity variations over time.
  • Using proprietary algorithms, it generates Dynamic Contrast Enhancement (DCE) parametric images.
  • These include the Ktrans transfer constant; extra-vascular, extra-cellular fractions (ve); and blood plasma fraction (vp), IVIM, and stretched exponential parameters such as alpha diffusion and distributed diffusion coefficient (DDC).

Benefits

  • Optimal post-processing algorithms produce validated output.
  • Aims to help predict treatment response for cancer therapy.
  • Vendor neutral and standardized image acquisition protocols promote high quality output.

Image examples

VE - DCE-1

To find out more about this solution or any of the other 140+ applications on the Blackford Platform, please book a discovery call with our team.

review image 1

Book a meeting

We’d welcome the opportunity to learn more about your AI needs and to explain how partnering with Blackford can drive efficiency and provide ongoing value.

Book a Meeting