ImageBiopsy Lab PANDA

Pediatric bone age and developmental assessment.

Overview

PANDA provides an automated method to estimate bone age according to Greulich & Pyle in a standardized form to facilitate the monitoring of child growth and development.

PANDA
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Features

PANDA is used on hand radiographs of children aged between 36 months and 192 months (girls) or 204 months (boys).

Radiological findings, measurements, and results including:

  • Pediatric bone age according to Greulich & Pyleu
  • Delayed / advanced bone age patient status
  • Height estimation according to Bayley & Pinneaum
  • Growth potential achieved

Benefits

  • Provides accurate automated bone age estimation: PANDA showed agreement with expert readers in BA assessment on a multiple-site cohort of U.S. children and adolescents, suggesting AI integration into the radiology workflow is possible and could lead to more efficient BA reading.¹
  • Demonstrates robust performance even in non strict p.a (oblique) projections of the hand and wrist.² 

Image examples

PANDA output-1

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¹DiFranco M, Chung TS, Mintz A, Wood J, Caudill KA, Hulett L. Automated Bone Age Assessment Across Multi-site U.S. Study: Agreement between AI and Expert Readers. Seminars in Musculoskeletal Radiology. 2022 Jun 1;

²Pape J, Hirsch W, Oliver Johannes Deffaa, DiFranco MD, Maciej Rosołowski, Gräfe D. Applicability and robustness of an artificial intelligence-based assessment for Greulich and Pyle bone age in a German cohort. RöFo. 2023 Dec 8;